BAFF promotes Th17 cells and aggravates experimental autoimmune encephalomyelitis.
BAFF, in addition to promoting B cell survival and differentiation, may affect T cells. The objective of this study was to determine the effect of BAFF on Th17 cell generation and its ramifications for the Th17 cell-driven disease, EAE.Th17 cells were increased in BAFF-Tg B6 (B6.BTg) mice and decrea...
Main Authors: | Xiaohui Zhou, Zanxian Xia, Qin Lan, Julie Wang, Wenru Su, Yuan-Ping Han, Huimin Fan, Zhongmin Liu, William Stohl, Song Guo Zheng |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3163640?pdf=render |
Similar Items
-
Gliotoxin Aggravates Experimental Autoimmune Encephalomyelitis by Triggering Neuroinflammation
by: Thais Fernanda de Campos Fraga-Silva, et al.
Published: (2019-07-01) -
Experimental Autoimmune Encephalomyelitis Development Is Aggravated by Candida albicans Infection
by: Thais F. C. Fraga-Silva, et al.
Published: (2015-01-01) -
Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis.
by: Helena S Domingues, et al.
Published: (2010-11-01) -
SKI Expression Suppresses Pathogenic Th17 Cell Response and Mitigates Experimental Autoimmune Encephalomyelitis
by: Ping Li, et al.
Published: (2021-07-01) -
Carnosol Modulates Th17 Cell Differentiation and Microglial Switch in Experimental Autoimmune Encephalomyelitis
by: Xing Li, et al.
Published: (2018-08-01)