Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence.
AIMS:Our aim was to evaluate, in a second data analysis of the prospective randomized controlled trial conducted by Austrian Urogynaecology Working Group, the effect of age, BMI and parity at the time of surgery on short- and long-term outcomes of women primarily treated for SUI (stress urinary inco...
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doaj-1c23da8d04d445269841879b13e599842020-11-25T02:40:11ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01138e020116710.1371/journal.pone.0201167Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence.Rosa Maria LaterzaKsenia HalpernDaniela UlrichAlexandra GrafKarl TamussinoWolfgang UmekAustrian TVT vs. TVT-O Study GroupAIMS:Our aim was to evaluate, in a second data analysis of the prospective randomized controlled trial conducted by Austrian Urogynaecology Working Group, the effect of age, BMI and parity at the time of surgery on short- and long-term outcomes of women primarily treated for SUI (stress urinary incontinence) with midurethral slings. METHODS:In the original study 554 patients received randomly a retropubic (TVT) or a transobturator midurethral (TVT-O) sling procedure. 480 (87%) and 277 (50%) patients were available for a follow-up efficacy evaluation at 3 months and 5 years respectively. RESULTS:Higher age and BMI at surgery appear to lead to a larger probability to have a positive stress test 5 years after surgery, but not after 3 months. Older patients seem to have a worse perception of improvement 5 years after surgery as compared to younger ones, as described by the PGI-I score. Age and BMI do not affect significantly the quality of life of women surgically treated for SUI, as reflected by the results of King´s Health Questionnaire. Parity does not seem to have any effect on objective and subjective surgical outcomes. CONCLUSIONS:Higher age and BMI at surgery have a detrimental influence on the objective cure rate at 5 years after midurethral sling surgery; higher age also has a negative influence on subjective long-term outcomes. However, these demographic parameters do not influence significantly the quality of life of patients after anti-incontinence surgery. Parity does not show any significant influence on success rate of midurethral sling.http://europepmc.org/articles/PMC6095512?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Rosa Maria Laterza Ksenia Halpern Daniela Ulrich Alexandra Graf Karl Tamussino Wolfgang Umek Austrian TVT vs. TVT-O Study Group |
spellingShingle |
Rosa Maria Laterza Ksenia Halpern Daniela Ulrich Alexandra Graf Karl Tamussino Wolfgang Umek Austrian TVT vs. TVT-O Study Group Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence. PLoS ONE |
author_facet |
Rosa Maria Laterza Ksenia Halpern Daniela Ulrich Alexandra Graf Karl Tamussino Wolfgang Umek Austrian TVT vs. TVT-O Study Group |
author_sort |
Rosa Maria Laterza |
title |
Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence. |
title_short |
Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence. |
title_full |
Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence. |
title_fullStr |
Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence. |
title_full_unstemmed |
Influence of age, BMI and parity on the success rate of midurethral slings for stress urinary incontinence. |
title_sort |
influence of age, bmi and parity on the success rate of midurethral slings for stress urinary incontinence. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2018-01-01 |
description |
AIMS:Our aim was to evaluate, in a second data analysis of the prospective randomized controlled trial conducted by Austrian Urogynaecology Working Group, the effect of age, BMI and parity at the time of surgery on short- and long-term outcomes of women primarily treated for SUI (stress urinary incontinence) with midurethral slings. METHODS:In the original study 554 patients received randomly a retropubic (TVT) or a transobturator midurethral (TVT-O) sling procedure. 480 (87%) and 277 (50%) patients were available for a follow-up efficacy evaluation at 3 months and 5 years respectively. RESULTS:Higher age and BMI at surgery appear to lead to a larger probability to have a positive stress test 5 years after surgery, but not after 3 months. Older patients seem to have a worse perception of improvement 5 years after surgery as compared to younger ones, as described by the PGI-I score. Age and BMI do not affect significantly the quality of life of women surgically treated for SUI, as reflected by the results of King´s Health Questionnaire. Parity does not seem to have any effect on objective and subjective surgical outcomes. CONCLUSIONS:Higher age and BMI at surgery have a detrimental influence on the objective cure rate at 5 years after midurethral sling surgery; higher age also has a negative influence on subjective long-term outcomes. However, these demographic parameters do not influence significantly the quality of life of patients after anti-incontinence surgery. Parity does not show any significant influence on success rate of midurethral sling. |
url |
http://europepmc.org/articles/PMC6095512?pdf=render |
work_keys_str_mv |
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