Small-cell lung cancer presenting as fatal pulmonary hemorrhage

Small-cell lung cancer (SCLC) is a lung cancer histological subtype unusual in its favorable response to cytotoxic chemotherapy. Life-threatening manifestations at presentation are rarely reported and should be an important clinical concern. We report a case of a 63-year-old man presenting with rapi...

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Main Authors: Lim Jun Hyeok, Ryu Jeong-Seon, Cho Sang Yong, Kim Hyun-Jung, Jeon Sang Hoon, Kim Jung Soo, Nam Hae-Seong, Cho Jae Hwa, Kwak Seung Min, Lee Hong Lyeol
Format: Article
Language:English
Published: De Gruyter 2018-03-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2018-0009
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spelling doaj-1c32491cac5f428ea8313fedd6045bb82021-10-02T17:52:40ZengDe GruyterOpen Medicine2391-54632018-03-01131646610.1515/med-2018-0009med-2018-0009Small-cell lung cancer presenting as fatal pulmonary hemorrhageLim Jun Hyeok0Ryu Jeong-Seon1Cho Sang Yong2Kim Hyun-Jung3Jeon Sang Hoon4Kim Jung Soo5Nam Hae-Seong6Cho Jae Hwa7Kwak Seung Min8Lee Hong Lyeol9Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Department of Internal Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, Republic of Korea, Tel: +82-32-890-3738, Fax: +82-32-882-6578Small-cell lung cancer (SCLC) is a lung cancer histological subtype unusual in its favorable response to cytotoxic chemotherapy. Life-threatening manifestations at presentation are rarely reported and should be an important clinical concern. We report a case of a 63-year-old man presenting with rapid-onset refractory severe thrombocytopenia, development of massive hemoptysis, and death from respiratory failure. This case provides clinicians a reference for this unusual presentation and carries clinical implications for managing SCLC patients.https://doi.org/10.1515/med-2018-0009small cell lung carcinomathrombocytopenialunghemorrhage
collection DOAJ
language English
format Article
sources DOAJ
author Lim Jun Hyeok
Ryu Jeong-Seon
Cho Sang Yong
Kim Hyun-Jung
Jeon Sang Hoon
Kim Jung Soo
Nam Hae-Seong
Cho Jae Hwa
Kwak Seung Min
Lee Hong Lyeol
spellingShingle Lim Jun Hyeok
Ryu Jeong-Seon
Cho Sang Yong
Kim Hyun-Jung
Jeon Sang Hoon
Kim Jung Soo
Nam Hae-Seong
Cho Jae Hwa
Kwak Seung Min
Lee Hong Lyeol
Small-cell lung cancer presenting as fatal pulmonary hemorrhage
Open Medicine
small cell lung carcinoma
thrombocytopenia
lung
hemorrhage
author_facet Lim Jun Hyeok
Ryu Jeong-Seon
Cho Sang Yong
Kim Hyun-Jung
Jeon Sang Hoon
Kim Jung Soo
Nam Hae-Seong
Cho Jae Hwa
Kwak Seung Min
Lee Hong Lyeol
author_sort Lim Jun Hyeok
title Small-cell lung cancer presenting as fatal pulmonary hemorrhage
title_short Small-cell lung cancer presenting as fatal pulmonary hemorrhage
title_full Small-cell lung cancer presenting as fatal pulmonary hemorrhage
title_fullStr Small-cell lung cancer presenting as fatal pulmonary hemorrhage
title_full_unstemmed Small-cell lung cancer presenting as fatal pulmonary hemorrhage
title_sort small-cell lung cancer presenting as fatal pulmonary hemorrhage
publisher De Gruyter
series Open Medicine
issn 2391-5463
publishDate 2018-03-01
description Small-cell lung cancer (SCLC) is a lung cancer histological subtype unusual in its favorable response to cytotoxic chemotherapy. Life-threatening manifestations at presentation are rarely reported and should be an important clinical concern. We report a case of a 63-year-old man presenting with rapid-onset refractory severe thrombocytopenia, development of massive hemoptysis, and death from respiratory failure. This case provides clinicians a reference for this unusual presentation and carries clinical implications for managing SCLC patients.
topic small cell lung carcinoma
thrombocytopenia
lung
hemorrhage
url https://doi.org/10.1515/med-2018-0009
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