Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China
Rosacea is a chronic inflammatory skin disease characterized by facial redness and bothersome symptoms. It can exert significant psychological effects and impair the quality of life of patients. To investigate the prevalence and risk predictors of anxiety and depression in rosacea patients, we condu...
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Frontiers Media S.A.
2021-06-01
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doaj-1c55afcad68047849794cc9d4d6a48e02021-06-16T06:31:34ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402021-06-011210.3389/fpsyt.2021.659171659171Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in ChinaMengting Chen0Mengting Chen1Mengting Chen2Mengting Chen3Zhili Deng4Zhili Deng5Zhili Deng6Zhili Deng7Yingxue Huang8Yingxue Huang9Yingxue Huang10Yingxue Huang11Ji Li12Ji Li13Ji Li14Ji Li15Ji Li16Department of Dermatology, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, ChinaKey Laboratary of Aging Biology of Hunan Province, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, ChinaKey Laboratary of Aging Biology of Hunan Province, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, ChinaKey Laboratary of Aging Biology of Hunan Province, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, ChinaNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, ChinaKey Laboratory of Organ Injury, Aging and Regenerative Medicine of Hunan Province, Changsha, ChinaKey Laboratary of Aging Biology of Hunan Province, Xiangya Hospital, Central South University, Changsha, ChinaDepartment of Dermatology, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaRosacea is a chronic inflammatory skin disease characterized by facial redness and bothersome symptoms. It can exert significant psychological effects and impair the quality of life of patients. To investigate the prevalence and risk predictors of anxiety and depression in rosacea patients, we conducted a cross-sectional study in an outpatient setting. Consecutive patients completed a questionnaire, which included questions on sociodemographic information and severity of signs and symptoms; they also completed the Patient Health Questionnaire and the Generalized Anxiety Disorder scale. Disease burden was assessed using Dermatology Life Quality Index (DLQI), Willing-to-Pay, and Time trade-off. Multivariate analysis was conducted to determine the risk factors for anxiety and depression. A total of 774 patients completed the survey. The prevalence of anxiety was 53.9% (95% CI: 50.4–57.4%) and that of depression was 58.1% (95% CI: 54.7–61.6%). The factors associated with anxiety were age, gender, the need to make appearances at work, severity of self-reported symptoms, the number of rosacea signs and adaptive behaviors, and disease burden. Depression was associated with younger age, more severe self-reported symptoms, more adaptive behaviors, and higher disease burden. After adjusting for demographics, the risk of anxiety or depression increased in young patients who had severe self-reported symptoms, high DLQI scores, and many adaptive behaviors. Taken together, there is a high prevalence of anxiety and depression among Chinese rosacea patients. Younger rosacea patients who have more severe self-reported symptoms and higher disease burden are prone to anxiety and depression.https://www.frontiersin.org/articles/10.3389/fpsyt.2021.659171/fulldepressionanxietydisease burdenrosaceaepidemiology |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mengting Chen Mengting Chen Mengting Chen Mengting Chen Zhili Deng Zhili Deng Zhili Deng Zhili Deng Yingxue Huang Yingxue Huang Yingxue Huang Yingxue Huang Ji Li Ji Li Ji Li Ji Li Ji Li |
spellingShingle |
Mengting Chen Mengting Chen Mengting Chen Mengting Chen Zhili Deng Zhili Deng Zhili Deng Zhili Deng Yingxue Huang Yingxue Huang Yingxue Huang Yingxue Huang Ji Li Ji Li Ji Li Ji Li Ji Li Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China Frontiers in Psychiatry depression anxiety disease burden rosacea epidemiology |
author_facet |
Mengting Chen Mengting Chen Mengting Chen Mengting Chen Zhili Deng Zhili Deng Zhili Deng Zhili Deng Yingxue Huang Yingxue Huang Yingxue Huang Yingxue Huang Ji Li Ji Li Ji Li Ji Li Ji Li |
author_sort |
Mengting Chen |
title |
Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China |
title_short |
Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China |
title_full |
Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China |
title_fullStr |
Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China |
title_full_unstemmed |
Prevalence and Risk Factors of Anxiety and Depression in Rosacea Patients: A Cross-Sectional Study in China |
title_sort |
prevalence and risk factors of anxiety and depression in rosacea patients: a cross-sectional study in china |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Psychiatry |
issn |
1664-0640 |
publishDate |
2021-06-01 |
description |
Rosacea is a chronic inflammatory skin disease characterized by facial redness and bothersome symptoms. It can exert significant psychological effects and impair the quality of life of patients. To investigate the prevalence and risk predictors of anxiety and depression in rosacea patients, we conducted a cross-sectional study in an outpatient setting. Consecutive patients completed a questionnaire, which included questions on sociodemographic information and severity of signs and symptoms; they also completed the Patient Health Questionnaire and the Generalized Anxiety Disorder scale. Disease burden was assessed using Dermatology Life Quality Index (DLQI), Willing-to-Pay, and Time trade-off. Multivariate analysis was conducted to determine the risk factors for anxiety and depression. A total of 774 patients completed the survey. The prevalence of anxiety was 53.9% (95% CI: 50.4–57.4%) and that of depression was 58.1% (95% CI: 54.7–61.6%). The factors associated with anxiety were age, gender, the need to make appearances at work, severity of self-reported symptoms, the number of rosacea signs and adaptive behaviors, and disease burden. Depression was associated with younger age, more severe self-reported symptoms, more adaptive behaviors, and higher disease burden. After adjusting for demographics, the risk of anxiety or depression increased in young patients who had severe self-reported symptoms, high DLQI scores, and many adaptive behaviors. Taken together, there is a high prevalence of anxiety and depression among Chinese rosacea patients. Younger rosacea patients who have more severe self-reported symptoms and higher disease burden are prone to anxiety and depression. |
topic |
depression anxiety disease burden rosacea epidemiology |
url |
https://www.frontiersin.org/articles/10.3389/fpsyt.2021.659171/full |
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