Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)).

Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4)).

BACKGROUND:Our previous studies indicated that MSC(CXCR4) improved cardiac function after myocardial infarction (MI). This study was aimed to investigate the specific role of MSC(CXCR4) in neovascularization of infarcted myocardium using a suicide gene approach. METHODS:MSCs were transduced with eit...

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Bibliographic Details
Main Authors: Jialiang Liang, Wei Huang, Xiyong Yu, Atif Ashraf, Kishore K Wary, Meifeng Xu, Ronald W Millard, Muhammad Ashraf, Yigang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460871?pdf=render

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