Association between DNA damage repair gene somatic mutations and immune‐related gene expression in ovarian cancer

Association between DNA damage repair gene somatic mutations and immune‐related gene expression in ovarian cancer

Abstract Background Defects in DNA damage repair (DDR) system may lead to genomic instability and manifest as increased immunogenicity. DDR deficiency is prevalent in ovarian cancer (OvCa); however, the association of DDR mutation with immune profiles in OvCa remains largely unknown. This knowledge...

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Bibliographic Details
Main Authors: Wenjuan Tian, Boer Shan, Yuzi Zhang, Yulan Ren, Shanhui Liang, Jing Zhao, Zhengyi Zhao, Guoqiang Wang, Xiaochen Zhao, Dongxian Peng, Rui Bi, Shangli Cai, Yuezong Bai, Huaying Wang
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Cancer Medicine
Subjects:
DNA damage repair
immunotherapy
mutation
ovarian cancer
Online Access:https://doi.org/10.1002/cam4.2849

Internet

https://doi.org/10.1002/cam4.2849

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