Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation
<p>Abstract</p> <p>Background</p> <p>Celiac disease (CD) is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins. The CD-toxicity of these proteins and their derived peptides is depending on the presence of specific T-ce...
Main Authors: | Salentijn Elma MJ, Mitea D, Goryunova Svetlana V, van der Meer Ingrid M, Padioleau Ismael, Gilissen Luud JWJ, Koning Frits, Smulders Marinus JM |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-06-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2164/13/277 |
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