Modeling DNA Methylation Profiles through a Dynamic Equilibrium between Methylation and Demethylation

Modeling DNA Methylation Profiles through a Dynamic Equilibrium between Methylation and Demethylation

DNA methylation is a heritable epigenetic mark that plays a key role in regulating gene expression. Mathematical modeling has been extensively applied to unravel the regulatory mechanisms of this process. In this study, we aimed to investigate DNA methylation by performing a high-depth analysis of p...

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Bibliographic Details
Main Authors:	Giulia De Riso, Damiano Francesco Giuseppe Fiorillo, Annalisa Fierro, Mariella Cuomo, Lorenzo Chiariotti, Gennaro Miele, Sergio Cocozza
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Biomolecules
Subjects:	DNA methylation DNA demethylation mathematical modeling statistical equilibrium cell-to-cell heterogeneity methylation profiles
Online Access:	https://www.mdpi.com/2218-273X/10/9/1271

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