Blood groups and malaria Grupos sanguíneos y malaria

• Main Authors: Fabiola Montoya, Marcos Restrepo, Astrid E. Montoya, William Rojas
• Format: Article
• Language: English
• Published: Universidade de São Paulo 1994-02-01
• Series: Revista do Instituto de Medicina Tropical de São Paulo
• Subjects: Malaria; Plasmodium; Blood groups
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46651994000100006

The possible relationship between erythrocyte antigens and the presence of malaria infection by P. vivax and P. falciparurn was sought in four different ethnic groups of two departments of Colombia. Malaria infection by P. falciparum was found in 91.4% of malaria infected blacks. No significant differences were found between the presence of malaria infection and ABO antigens. In the other blood groups, it was observed that groups MNSs conferred black people a greater Rr for malaria by both species of Plasmodium and that Duffy-negative blacks and indians appeared to be resistant to P. vivax infection. A predominance of P. vivax infection was observed in Katio indians while P.falciparum was predominant in Kuna indians; the reason for this finding still needs to be explored.<br>Con el presente estudio se evalúa la relación existente entre la infección por P. vivax y P. falciparum y los antígenos eritrocitos de cuatro diferentes grupos étnicos en Colombia. P. falciparum se encontró causando malaria en el 91.4% de los individuos de raza negra que tuvieron malaria. No hubo diferenciais significativas entre la infección malaria y los antígenos ABO. La presencia de grupos del sistema MNSs en persona de raza negra confiere un mayor riesgo relativo por la infección para las dos especies de Plasmodium, igualmente hay mayor riesgo cuando se pertenece a la raza negra o indígena y el grupo Duffy es negativo. La infección por P. vivax predomina en los indios Katios pero en los Kunas prevalece P. falciparum.