The role of ultrasonography in methotrexate therapy for ectopic pregnancy
Medical management of ectopic pregnancy with methotrexate, an antimetabolite of folic acid, is an important alternative to surgical treatment, as it ensures a similar outcome whilst being far less invasive. Ultrasound evaluation does not only facilitate an accurate diagnosis, but also helps to se...
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Format: | Article |
Language: | English |
Published: |
Medical Communications Sp. z o.o.
2018-06-01
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Series: | Journal of Ultrasonography |
Subjects: | |
Online Access: | http://jultrason.pl/index.php/issues/volume-18-no-73/the-role-of-ultrasonography-in-methotrexate-therapy-for-ectopic-pregnancy?aid=626 |
Summary: | Medical management of ectopic pregnancy with methotrexate, an antimetabolite of folic
acid, is an important alternative to surgical treatment, as it ensures a similar outcome whilst
being far less invasive. Ultrasound evaluation does not only facilitate an accurate diagnosis,
but also helps to select patients most likely to benefit from methotrexate treatment, as
opposed to those with a high likelihood of failure of medical management, who are thus
eligible for primary surgical treatment. Ultrasound also allows to monitor the outcome of
methotrexate therapy. This study is a review of literature regarding the management of ectopic
pregnancy with methotrexate. Such ultrasound findings as the size of the ectopic mass,
presence of fetal heart rate and free fluid have been confirmed as effective eligibility criteria
for therapy with methotrexate. In the future, possibly also endometrial stripe thickness and
the vascularity of the ectopic mass may be considered predictive of successful methotrexate
therapy. The initial increase in size of the ectopic mass following methotrexate therapy
confirms its effectiveness, and should not prompt concern. |
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ISSN: | 2084-8404 2451-070X |