Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

Diethyl malonate-based fluorescent probe NE-N2H4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N2H4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N2H4 can be operated to detect hydrazine in liv...

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Bibliographic Details
Main Authors: Jianbo Qu, Zhi-Hao Zhang, Haitao Zhang, Zhen-Tao Weng, Jian-Yong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Chemistry
Subjects:
fluorescent probe
hydrazine
Stokes shift
gas detection
cell imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2020.602125/full
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spelling doaj-1cd0b0db4e444e51a79b1d4e2e4cb7c92021-03-18T05:29:20ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462021-03-01810.3389/fchem.2020.602125602125Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes ShiftJianbo QuZhi-Hao ZhangHaitao ZhangZhen-Tao WengJian-Yong WangDiethyl malonate-based fluorescent probe NE-N2H4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N2H4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N2H4 can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N2H4 might be used to monitor hydrazine in biosamples and environmental problem.https://www.frontiersin.org/articles/10.3389/fchem.2020.602125/fullfluorescent probehydrazineStokes shiftgas detectioncell imaging
collection DOAJ
language English
format Article
sources DOAJ
author Jianbo Qu
Zhi-Hao Zhang
Haitao Zhang
Zhen-Tao Weng
Jian-Yong Wang
spellingShingle Jianbo Qu
Zhi-Hao Zhang
Haitao Zhang
Zhen-Tao Weng
Jian-Yong Wang
Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
Frontiers in Chemistry
fluorescent probe
hydrazine
Stokes shift
gas detection
cell imaging
author_facet Jianbo Qu
Zhi-Hao Zhang
Haitao Zhang
Zhen-Tao Weng
Jian-Yong Wang
author_sort Jianbo Qu
title Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_short Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_full Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_fullStr Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_full_unstemmed Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift
title_sort diethyl malonate-based turn-on chemical probe for detecting hydrazine and its bio-imaging and environmental applications with large stokes shift
publisher Frontiers Media S.A.
series Frontiers in Chemistry
issn 2296-2646
publishDate 2021-03-01
description Diethyl malonate-based fluorescent probe NE-N2H4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N2H4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N2H4 can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N2H4 might be used to monitor hydrazine in biosamples and environmental problem.
topic fluorescent probe
hydrazine
Stokes shift
gas detection
cell imaging
url https://www.frontiersin.org/articles/10.3389/fchem.2020.602125/full
work_keys_str_mv AT jianboqu diethylmalonatebasedturnonchemicalprobefordetectinghydrazineanditsbioimagingandenvironmentalapplicationswithlargestokesshift
AT zhihaozhang diethylmalonatebasedturnonchemicalprobefordetectinghydrazineanditsbioimagingandenvironmentalapplicationswithlargestokesshift
AT haitaozhang diethylmalonatebasedturnonchemicalprobefordetectinghydrazineanditsbioimagingandenvironmentalapplicationswithlargestokesshift
AT zhentaoweng diethylmalonatebasedturnonchemicalprobefordetectinghydrazineanditsbioimagingandenvironmentalapplicationswithlargestokesshift
AT jianyongwang diethylmalonatebasedturnonchemicalprobefordetectinghydrazineanditsbioimagingandenvironmentalapplicationswithlargestokesshift
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