Deregulation of Interferon Signaling in Malignant Cells

Deregulation of Interferon Signaling in Malignant Cells

Interferons (IFNs) are a family of cytokines with potent antiproliferative, antiviral, and immunomodulatory properties. Much has been learned about IFNs and IFN-activated signaling cascades over the last 50 years. Due to their potent antitumor effects in vitro and in vivo, recombinant IFNs have been...

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Bibliographic Details
Main Authors: Leonidas C. Platanias, Surinder Kaur, Efstratios Katsoulidis
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Series:Pharmaceuticals
Subjects:
interferon
signaling pathways
cancer
Online Access:http://www.mdpi.com/1424-8247/3/2/406/

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