Full-Length Recombinant hSP-D Binds and Inhibits SARS-CoV-2
SARS-CoV-2 infection of host cells is driven by binding of the SARS-CoV-2 spike-(S)-protein to lung type II pneumocytes, followed by virus replication. Surfactant protein SP-D, member of the front-line immune defense of the lungs, binds glycosylated structures on invading pathogens such as viruses t...
Main Authors: | Raquel Arroyo, Shawn N. Grant, Miriam Colombo, Lucia Salvioni, Fabio Corsi, Marta Truffi, Davide Ottolina, Brett Hurst, Marc Salzberg, Davide Prosperi, Paul S. Kingma |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/8/1114 |
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