Sex differences in the effect of the FKBP5 inhibitor SAFit2 on anxiety and stress-induced reinstatement following cocaine self-administration
Cocaine use and withdrawal prompt stress system responses. Stress and the negative affective state produced by cocaine withdrawal are major triggers for relapse. FKBP5 is a co-chaperone of the glucocorticoid receptor and regulates HPA axis negative feedback. The role of FKBP5 in cocaine-related beha...
Main Authors: | Krista L. Connelly, Cassandra C. Wolsh, Jeffrey L. Barr, Michael Bauder, Felix Hausch, Ellen M. Unterwald |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-11-01
|
Series: | Neurobiology of Stress |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352289520300229 |
Similar Items
-
FKBP Ligands—Where We Are and Where to Go?
by: Jürgen M. Kolos, et al.
Published: (2018-12-01) -
Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs
by: Max L. Pöhlmann, et al.
Published: (2018-11-01) -
Optogenetic dissection of basolateral amygdala projections during cue-induced reinstatement of cocaine seeking.
by: Michael T. Stefanik, et al.
Published: (2013-12-01) -
The Many Faces of FKBP51
by: Andreas Hähle, et al.
Published: (2019-01-01) -
An extended amygdala-midbrain circuit controlling cocaine withdrawal-induced anxiety and reinstatement
by: Bartas, K., et al.
Published: (2022)