Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens

Gene Expression Analysis of an EGFR Indirectly Related Pathway Identified PTEN and MMP9 as Reliable Diagnostic Markers for Human Glial Tumor Specimens

In this study the mRNA levels of five EGFR indirectly related genes, EGFR, HB-EGF, ADAM17, PTEN, and MMP9, have been assessed by Real-time PCR in a panel of 37 glioblastoma multiforme specimens and in 5 normal brain samples; as a result, in glioblastoma, ADAM17 and PTEN expression was significantly...

Full description

Bibliographic Details
Main Authors: Sergio Comincini, Mayra Paolillo, Giulia Barbieri, Silvia Palumbo, Elena Sbalchiero, Alberto Azzalin, Marika A. Russo, Sergio Schinelli
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2009/924565

Similar Items

Similar Items