The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran
Increasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pne...
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2020-06-01
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doaj-1d13975acd3a4e43a7993a2c36ef184d2020-11-25T04:05:26ZengResearch Center for Rational Use of Drugs (RCRUD)Journal of Pharmaceutical Care2322-46302322-45092020-06-018387295The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of IranSaeed MehralinejadianMandana IzadpanahFarhad SoltaniSepideh SayadiMaryam AghakouchakzadehIncreasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pneumonia were included in the study. The prevalence of resistant gram-negative microorganisms was studied through reported laboratory antibiogram results of cultures. Based on the results of the study, From 373 hospitalized patients, 38 (10.2%) were diagnosed with VAP. From the 57 respiratory cultures performed, overall 90 microorganisms were isolated, from which Enterobacter with 36 cases (39.5%) and E.Coli with 28 cases (30.7%) was most frequently compared to other organisms. Of the 90 organisms responsible for the infection, 43 cases (47.2%) were MDR microorganisms and 47 (51.6%) were XDR microorganisms. Enterobacter and E.Coli were the most prevalent MDR microorganisms with 17 cases (39.5%) and 13 (30.2%), respectively. Also, these two microorganisms were the most abundant XDR microorganisms with 19 cases (40.4%) and 15 (31.9%), respectively. The results show the requirement of robust antibiotic monitoring and the optimization of antibiotic use in order to prevent the progression of antibiotic resistance in these units.https://jpc.tums.ac.ir/index.php/jpc/article/view/295resistanceventilator-associated pneumoniaintensive care unitsgram-negative microorganisms |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Saeed Mehralinejadian Mandana Izadpanah Farhad Soltani Sepideh Sayadi Maryam Aghakouchakzadeh |
spellingShingle |
Saeed Mehralinejadian Mandana Izadpanah Farhad Soltani Sepideh Sayadi Maryam Aghakouchakzadeh The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran Journal of Pharmaceutical Care resistance ventilator-associated pneumonia intensive care units gram-negative microorganisms |
author_facet |
Saeed Mehralinejadian Mandana Izadpanah Farhad Soltani Sepideh Sayadi Maryam Aghakouchakzadeh |
author_sort |
Saeed Mehralinejadian |
title |
The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
title_short |
The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
title_full |
The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
title_fullStr |
The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
title_full_unstemmed |
The Prevalence of Gram-Negative Microorganisms Isolated from VentilatorAssociated Pneumonia Patients in the Intensive Care Units of Southwest of Iran |
title_sort |
prevalence of gram-negative microorganisms isolated from ventilatorassociated pneumonia patients in the intensive care units of southwest of iran |
publisher |
Research Center for Rational Use of Drugs (RCRUD) |
series |
Journal of Pharmaceutical Care |
issn |
2322-4630 2322-4509 |
publishDate |
2020-06-01 |
description |
Increasing microbial resistance is a severe threat to global public health. One of the most common diseases in the intensive care unit is ventilator-associated pneumonia. This study was carried out from January to March 2018, at the Golestan Hospital of Ahvaz. Patients with ventilator-associated pneumonia were included in the study. The prevalence of resistant gram-negative microorganisms was studied through reported laboratory antibiogram results of cultures.
Based on the results of the study, From 373 hospitalized patients, 38 (10.2%) were diagnosed with VAP. From the 57 respiratory cultures performed, overall 90 microorganisms were isolated, from which Enterobacter with 36 cases (39.5%) and E.Coli with 28 cases (30.7%) was most frequently compared to other organisms. Of the 90 organisms responsible for the infection, 43 cases (47.2%) were MDR microorganisms and 47 (51.6%) were XDR microorganisms. Enterobacter and E.Coli were the most prevalent MDR microorganisms with 17 cases (39.5%) and 13 (30.2%), respectively. Also, these two microorganisms were the most abundant XDR microorganisms with 19 cases (40.4%) and 15 (31.9%), respectively.
The results show the requirement of robust antibiotic monitoring and the optimization of antibiotic use in order to prevent the progression of antibiotic resistance in these units. |
topic |
resistance ventilator-associated pneumonia intensive care units gram-negative microorganisms |
url |
https://jpc.tums.ac.ir/index.php/jpc/article/view/295 |
work_keys_str_mv |
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