Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities

Interaction between Shiga Toxin and Monoclonal Antibodies: Binding Characteristics and in Vitro Neutralizing Abilities

Monoclonal antibodies (MAbs) have been employed either for diagnosis or treatment of infections caused by different pathogens. Specifically for Shiga toxin-producing Escherichia coli (STEC), numerous immunoassays have been developed for STEC diagnosis, showing variability in sensitivity and specific...

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Bibliographic Details
Main Authors: Letícia B. Rocha, Daniela E. Luz, Claudia T. P. Moraes, Andressa Caravelli, Irene Fernandes, Beatriz E. C. Guth, Denise S. P. Q. Horton, Roxane M. F. Piazza
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Toxins
Subjects:
Stx1
Stx2
monoclonal antibodies
binding
stability
detection
neutralizing ability
specificity
Online Access:http://www.mdpi.com/2072-6651/4/9/729

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