SubVis: an interactive R package for exploring the effects of multiple substitution matrices on pairwise sequence alignment

Understanding how proteins mutate is critical to solving a host of biological problems. Mutations occur when an amino acid is substituted for another in a protein sequence. The set of likelihoods for amino acid substitutions is stored in a matrix and input to alignment algorithms. The quality of the...

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Bibliographic Details
Main Authors: Scott Barlowe, Heather B. Coan, Robert T. Youker
Format: Article
Language:English
Published: PeerJ Inc. 2017-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3492.pdf

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