Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data

Dimensionality reduction is used to make the analysis of single-cell RNA sequencing data more efficient. Here the authors propose a method, EDGE, which simultaneously carries out dimensionality reduction and feature gene extraction.

Bibliographic Details
Main Authors: Xiaoxiao Sun, Yiwen Liu, Lingling An
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19465-7
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spelling doaj-1d299ddc8b48413b83824aa45ed590a82021-05-11T08:59:03ZengNature Publishing GroupNature Communications2041-17232020-11-011111910.1038/s41467-020-19465-7Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq dataXiaoxiao Sun0Yiwen Liu1Lingling An2Department of Epidemiology and Biostatistics, University of ArizonaDepartment of Epidemiology and Biostatistics, University of ArizonaDepartment of Epidemiology and Biostatistics, University of ArizonaDimensionality reduction is used to make the analysis of single-cell RNA sequencing data more efficient. Here the authors propose a method, EDGE, which simultaneously carries out dimensionality reduction and feature gene extraction.https://doi.org/10.1038/s41467-020-19465-7
collection DOAJ
language English
format Article
sources DOAJ
author Xiaoxiao Sun
Yiwen Liu
Lingling An
spellingShingle Xiaoxiao Sun
Yiwen Liu
Lingling An
Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
Nature Communications
author_facet Xiaoxiao Sun
Yiwen Liu
Lingling An
author_sort Xiaoxiao Sun
title Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
title_short Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
title_full Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
title_fullStr Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
title_full_unstemmed Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
title_sort ensemble dimensionality reduction and feature gene extraction for single-cell rna-seq data
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2020-11-01
description Dimensionality reduction is used to make the analysis of single-cell RNA sequencing data more efficient. Here the authors propose a method, EDGE, which simultaneously carries out dimensionality reduction and feature gene extraction.
url https://doi.org/10.1038/s41467-020-19465-7
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AT yiwenliu ensembledimensionalityreductionandfeaturegeneextractionforsinglecellrnaseqdata
AT linglingan ensembledimensionalityreductionandfeaturegeneextractionforsinglecellrnaseqdata
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