Stress responsive miR-31 is a major modulator of mouse intestinal stem cells during regeneration and tumorigenesis

Stress responsive miR-31 is a major modulator of mouse intestinal stem cells during regeneration and tumorigenesis

Intestinal regeneration and tumorigenesis are believed to be driven by intestinal stem cells (ISCs). Elucidating mechanisms underlying ISC activation during regeneration and tumorigenesis can help uncover the underlying principles of intestinal homeostasis and disease including colorectal cancer. He...

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Bibliographic Details
Main Authors: Yuhua Tian, Xianghui Ma, Cong Lv, Xiaole Sheng, Xiang Li, Ran Zhao, Yongli Song, Thomas Andl, Maksim V Plikus, Jinyue Sun, Fazheng Ren, Jianwei Shuai, Christopher J Lengner, Wei Cui, Zhengquan Yu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
miR-31
intestinal stem cell
colorectal cancer
regeneration
Wnt
BMP
Online Access:https://elifesciences.org/articles/29538

Internet

https://elifesciences.org/articles/29538

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