Comprehensive Profiling of Hypoxia-Related miRNAs Identifies miR-23a-3p Overexpression as a Marker of Platinum Resistance and Poor Prognosis in High-Grade Serous Ovarian Cancer
The onset of chemo-resistant recurrence represents the principal cause of high-grade serous ovarian carcinoma (HGSOC) death. HGSOC masses are characterized by a hypoxic microenvironment, which contributes to the development of this chemo-resistant phenotype. Hypoxia regulated-miRNAs (HRMs) represent...
Main Authors: | Paola Todeschini, Elisa Salviato, Chiara Romani, Vittoria Raimondi, Francesco Ciccarese, Federico Ferrari, Germana Tognon, Sergio Marchini, Maurizio D’Incalci, Laura Zanotti, Antonella Ravaggi, Franco Odicino, Enrico Sartori, Donna M. D’Agostino, Michele Samaja, Chiara Romualdi, Eliana Bignotti |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/13/3358 |
Similar Items
-
miR-15/107 microRNA Gene Group: Characteristics and Functional Implications in Cancer
by: Chiara Turco, et al.
Published: (2020-06-01) -
Evidence That Regulation of Pri-miRNA/miRNA Expression Is Not a General Rule of miPEPs Function in Humans
by: Anne Prel, et al.
Published: (2021-03-01) -
miRBaseConverter: an R/Bioconductor package for converting and retrieving miRNA name, accession, sequence and family information in different versions of miRBase
by: Taosheng Xu, et al.
Published: (2018-12-01) -
miR-146 and miR-155: Two Key Modulators of Immune Response and Tumor Development
by: Ugo Testa, et al.
Published: (2017-06-01) -
Mi oíslo
by: Mitja Skubic
Published: (2006-12-01)