| Summary: | Unicystic ameloblastoma is considered a less aggressive variant of ameloblastoma with clinical and radiographic features mimicking a cyst. Herein, we present a case of unicystic ameloblastoma in a 20-year-old female who was clinically and radiographically diagnosed as an odontogenic cyst. Unicystic ameloblastoma and its subtypes are reviewed with special emphasis on the mural variant. The main aim of this case report is to highlight (1) the need of including an odontogenic tumor in the differential diagnosis of the unilocular, well-circumscribed radiolucent lesion by the clinicians (2) importance of serial sectioning of the specimen to identify the mural component if any present, and (3) following resection as the mode of treatment.
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