Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

The vast majority of neurodegenerative pathologies stem from the formation of toxic oligomers and aggregates composed of wrongly folded proteins. These protein complexes can be released from pathogenic cells and enthralled by other cells, causing the formation of new aggregates in a prion-like manne...

Full description

Bibliographic Details
Main Authors: Vladimir F. Lazarev, Elena R. Mikhaylova, Irina V. Guzhova, Boris A. Margulis
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Neuroscience
Subjects:
conformational neurodegenerative pathologies
cell-to-cell transmission
molecular chaperones
aggregation
prions
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00277/full

Similar Items

Similar Items