Glucocorticoids in Leprosy Reversal reaction

Leprosy is a disease that is caused by Mycobacterium leprae which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy regimen; however, this therapy might cause leprosy reactions in the patients. There are several types of lepromatous reaction: type 1 reaction,...

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Bibliographic Details
Main Authors: Yuniati Renni, Khrisna Matthew Brian
Format: Article
Language:English
Published: Sciendo 2019-09-01
Series:Serbian Journal of Dermatology and Venereology
Subjects:
Online Access:https://doi.org/10.2478/sjdv-2019-0011
Description
Summary:Leprosy is a disease that is caused by Mycobacterium leprae which results in lots of disabilities in the patients. Leprosy is treated by multi-drug therapy regimen; however, this therapy might cause leprosy reactions in the patients. There are several types of lepromatous reaction: type 1 reaction, type 2 reaction and neuritis. Type 1 reaction mainly occurs in BB, BL and BT forms of leprosy and is characterized by exacerbation of preexisting lesions. The therapy of this reaction according to the WHO guideline is corticosteroid therapy. This article will explain several key points related to the corticosteroid therapy in leprosy reversal reactions, including the side effects and alternative therapies available.
ISSN:1821-0902
2406-0631