Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire
Helen Crocker, Crispin Jenkinson, Michele Peters Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK Background: Coeliac-specific measures have been criticized for not complying with current guidance on the development of patient-reported outcome...
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doaj-1d7b41cd38cf436ba0eb970e7b2806d12020-11-24T21:59:01ZengDove Medical PressPatient Related Outcome Measures1179-271X2018-07-01Volume 921122039140Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment QuestionnaireCrocker HJenkinson CPeters MHelen Crocker, Crispin Jenkinson, Michele Peters Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK Background: Coeliac-specific measures have been criticized for not complying with current guidance on the development of patient-reported outcome measures (PROMs). The aim of this study was to develop a measure to assess health-related quality of life in adults with coeliac disease (CD), in accordance with current guidance for PROM development. Methods: In-depth qualitative interviews were conducted with adults with CD. A thematic analysis was undertaken to develop a coding framework. All interviews were analyzed according to this framework. Interviewing continued until data saturation was achieved. Candidate items were developed on the basis of the interview findings. Results: The analysis revealed 6 themes: 1) symptoms, 2) gluten-free diet, 3) emotional health, 4) impact on activities, 5) relationships, and 6) financial issues. Data saturation was reached after 8 interviews, but a total of 23 interviews were conducted to include a wide enough range of diverse participants. From the themes, 64 candidate items (9 for symptoms, 15 for emotional health, 16 for gluten-free diet, 7 for relationships, 12 for impact on activities, and 5 for financial issues) were developed to form the first draft of the Coeliac Disease Assessment Questionnaire (CDAQ). Conclusion: The 64 items reflect all the issues of importance to people with CD. Next, these items will be pretested and refined to lead to a shorter draft version of the CDAQ before it is administered in a survey to produce a final version with subscales. Keywords: coeliac disease, quality of life, patient-reported outcome measure, item development, qualitative, content validity, conceptual frameworkhttps://www.dovepress.com/quality-of-life-in-coeliac-disease-qualitative-interviews-to-develop-c-peer-reviewed-article-PROMcoeliac diseasequality of lifepatient-reported outcome measureitem developmentqualitative. |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Crocker H Jenkinson C Peters M |
spellingShingle |
Crocker H Jenkinson C Peters M Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire Patient Related Outcome Measures coeliac disease quality of life patient-reported outcome measure item development qualitative. |
author_facet |
Crocker H Jenkinson C Peters M |
author_sort |
Crocker H |
title |
Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire |
title_short |
Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire |
title_full |
Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire |
title_fullStr |
Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire |
title_full_unstemmed |
Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire |
title_sort |
quality of life in coeliac disease: qualitative interviews to develop candidate items for the coeliac disease assessment questionnaire |
publisher |
Dove Medical Press |
series |
Patient Related Outcome Measures |
issn |
1179-271X |
publishDate |
2018-07-01 |
description |
Helen Crocker, Crispin Jenkinson, Michele Peters Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK Background: Coeliac-specific measures have been criticized for not complying with current guidance on the development of patient-reported outcome measures (PROMs). The aim of this study was to develop a measure to assess health-related quality of life in adults with coeliac disease (CD), in accordance with current guidance for PROM development. Methods: In-depth qualitative interviews were conducted with adults with CD. A thematic analysis was undertaken to develop a coding framework. All interviews were analyzed according to this framework. Interviewing continued until data saturation was achieved. Candidate items were developed on the basis of the interview findings. Results: The analysis revealed 6 themes: 1) symptoms, 2) gluten-free diet, 3) emotional health, 4) impact on activities, 5) relationships, and 6) financial issues. Data saturation was reached after 8 interviews, but a total of 23 interviews were conducted to include a wide enough range of diverse participants. From the themes, 64 candidate items (9 for symptoms, 15 for emotional health, 16 for gluten-free diet, 7 for relationships, 12 for impact on activities, and 5 for financial issues) were developed to form the first draft of the Coeliac Disease Assessment Questionnaire (CDAQ). Conclusion: The 64 items reflect all the issues of importance to people with CD. Next, these items will be pretested and refined to lead to a shorter draft version of the CDAQ before it is administered in a survey to produce a final version with subscales. Keywords: coeliac disease, quality of life, patient-reported outcome measure, item development, qualitative, content validity, conceptual framework |
topic |
coeliac disease quality of life patient-reported outcome measure item development qualitative. |
url |
https://www.dovepress.com/quality-of-life-in-coeliac-disease-qualitative-interviews-to-develop-c-peer-reviewed-article-PROM |
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