Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone

Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone

Neurogenesis continues in the ventricular-subventricular zone (V-SVZ) of the adult forebrain from quiescent neural stem cells (NSCs). V-SVZ NSCs are a reservoir for new olfactory bulb (OB) neurons that migrate through the rostral migratory stream (RMS). To generate neurons, V-SVZ NSCs need to activa...

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Bibliographic Details
Main Authors: Anna Engler, Chiara Rolando, Claudio Giachino, Ichiko Saotome, Andrea Erni, Callum Brien, Runrui Zhang, Ursula Zimber-Strobl, Freddy Radtke, Spyros Artavanis-Tsakonas, Angeliki Louvi, Verdon Taylor
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Cell Reports
Subjects:
quiescence
neural stem cells
niche
neurogenesis
olfactory bulb
Notch
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717319319

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