Targeting the innate immune system as immunotherapy for Acute Myeloid Leukemia (AML)

Targeting the innate immune system as immunotherapy for Acute Myeloid Leukemia (AML)

Because of its disseminated nature and lack of tumor-draining lymph nodes, acute myeloid leukemia (AML) likely employs unique immune evasion strategies as compared to solid malignancies. Targeting these unique mechanisms may result in improved immunotherapeutic approaches. Emerging data suggests tha...

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Bibliographic Details
Main Authors: Emily Kathleen Curran, Leticia eCorrales, Justin eKline
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Oncology
Subjects:
Calreticulin
innate immunity
Acute Myeloid Leukemia
stat3
STING
TLRs (Toll-like receptors)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00083/full

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