A moderate response to plasmapheresis in nephrogenic systemic fibrosis

• Main Authors: Pelin Ustuner, Ozlem Karadag Kose, A. Tulin Gulec, Ozlem Ozen
• Format: Article
• Language: English
• Published: MDPI AG 2011-11-01
• Series: Clinics and Practice
• Subjects: nephrogenic fibrosing dermopathy; plasmapheresis; transforming growth factors.
• Online Access: https://www.clinicsandpractice.org/index.php/cp/article/view/182

Nephrogenic systemic fibrosis (NSF) is a recently identified idiopathic cutaneous fibrosing disorder that occurs in the setting of renal failure. The disease initially called nephrogenic fibrosing dermopathy is closely linked to exposure to gadolinium-based contrast media used during magnetic resonance imaging in patients with renal insufficiency. Although little is known about the pathogenesis of this disease, the increased expression of transforming growth factor-beta has been demonstrated recently. Herein, we present a case of NSF was partially treated due to a moderate and temporary response to plasmapheresis with no recurrence for 6 months, but returned at the end of 6th month.