Application of immunotherapy based on dendritic cells stimulated by tumor cell-derived exosomes in a syngeneic breast tumor mouse model

Application of immunotherapy based on dendritic cells stimulated by tumor cell-derived exosomes in a syngeneic breast tumor mouse model

We here evaluated the therapeutic effect of tumor cell-derived exosomes (TEXs)-stimulated dendritic cells (DCs) in a syngeneic orthotopic breast tumor model. The DC line DC2.4 and breast cancer cell line E0771 originally isolated from C57BL/6 mice were used. E0771 cells stably expressing the exosoma...

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Bibliographic Details
Main Authors: Yin Ji Piao, So-Hyun Yoon, Hoe Suk Kim, Woo Kyung Moon, Wonshik Han
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Breast cancer
Exosomes
Dendritic cells
Cancer immunotherapy
Syngeneic tumor model
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580821002302

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