A review on the development of urease inhibitors as antimicrobial agents against pathogenic bacteria

Ureases are enzymes that hydrolyze urea into ammonium and carbon dioxide. They have received considerable attention due to their impacts on living organism health, since the urease activity in microorganisms, particularly in bacteria, are potential causes and/or factors contributing to the persisten...

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Bibliographic Details
Main Authors: Yuri F. Rego, Marcelo P. Queiroz, Tiago O. Brito, Priscila G. Carvalho, Vagner T. de Queiroz, Ângelo de Fátima, Fernando Macedo Jr.
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Advanced Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123218300560