Renal Synovial Sarcoma in a Young Pregnant Lady: A Case Report and Clinico-Pathological Profile
Synovial sarcoma is a soft tissue neoplasm with clearly defined histologic, immunohistochemical and molecular features. These tumours usually arise in the extremities of young adults. Their occurrence in the kidney is extremely rare. A 25-year-old pregnant lady in her first trimester was incidenta...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/10245/25733_CE[Ra]_F(Sh)_PF1(NE_DS_SS)_PFA(NC).pdf |
| Summary: | Synovial sarcoma is a soft tissue neoplasm with clearly defined histologic, immunohistochemical and molecular features. These
tumours usually arise in the extremities of young adults. Their occurrence in the kidney is extremely rare. A 25-year-old pregnant
lady in her first trimester was incidentally found to have a left renal mass on perinatal ultrasonography. MRI showed a well
encapsulated, heterointense mass replacing the left kidney. Following medical termination of her pregnancy, a radical nephrectomy
was performed. Histopathology revealed a primary synovial cell sarcoma of the kidney. Postoperatively, she received ifosfamide
based adjuvant chemotherapy. This report highlights the challenges involved in the diagnosis of this extremely rare neoplasm. A
high index of clinical suspicion, complimented by the use of immunohistochemistry and cytogenetics during histopathological
analysis aide in the diagnosis. Aggressive management with a combination of complete surgical extirpation and chemotherapy
gives the best results. |
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| ISSN: | 2249-782X 0973-709X |