BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT
Due to the permanent discordance between the number of available liver grafts and the number of cases on the waiting lists, attention was focused on developing different solutions in order to increase the number of grafts. Once the technique of living donor has been proposed, the number of grafts...
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2019-09-01
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doaj-1df0ed10dba64762a6a4afdf66988e302021-09-02T21:17:40ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2019-09-0166323924210.37897/RMJ.2019.3.12BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANTNicolae Bacalbasa0Irina Balescu1Adina Croitoru2Simona Dima3Mihaela Vilcu4Iulian Brezean5“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Ion Cantacuzino” Clinical Hospital, Bucharest, Romania“Ponderas” Academic Hospital, Bucharest, RomaniaFundeni Clinical Institute, Bucharest, Romania; Faculty of Medicine, “Titu Maiorescu” University, Bucharest, RomaniaFundeni Clinical Institute, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Ion Cantacuzino” Clinical Hospital, Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; “Ion Cantacuzino” Clinical Hospital, Bucharest, RomaniaDue to the permanent discordance between the number of available liver grafts and the number of cases on the waiting lists, attention was focused on developing different solutions in order to increase the number of grafts. Once the technique of living donor has been proposed, the number of grafts increased but the gap between the number of available grafts and the cases on the waiting list is still significant. Therefore attention was focused on finding out other solutions such as splitting the graft or performing a domino liver transplant. The procedure of domino transplant consists of harvesting a graft from a young patient with metabolic disorders in which a healthy graft will be used and implants it to a marginal receiver. The method seems to associate minimal risks for the marginal donor to develop the metabolic disorder especially if the donor suffers from familial amyloid polyneuropathy; however, ethical issues in such cases are obvious. The aim of this paper is to analyse both the benefits of domino liver transplant and the ethical issues of the procedure.https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.3/RMJ_2019_3_Art-12.pdfdomino liver transplantmetabolic disorderssurvivalethical issues |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Nicolae Bacalbasa Irina Balescu Adina Croitoru Simona Dima Mihaela Vilcu Iulian Brezean |
spellingShingle |
Nicolae Bacalbasa Irina Balescu Adina Croitoru Simona Dima Mihaela Vilcu Iulian Brezean BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT Romanian Medical Journal domino liver transplant metabolic disorders survival ethical issues |
author_facet |
Nicolae Bacalbasa Irina Balescu Adina Croitoru Simona Dima Mihaela Vilcu Iulian Brezean |
author_sort |
Nicolae Bacalbasa |
title |
BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT |
title_short |
BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT |
title_full |
BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT |
title_fullStr |
BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT |
title_full_unstemmed |
BENEFITS AND ETHICAL ISSUES IN DOMINO LIVER TRANSPLANT |
title_sort |
benefits and ethical issues in domino liver transplant |
publisher |
Amaltea Medical Publishing House |
series |
Romanian Medical Journal |
issn |
1220-5478 2069-606X |
publishDate |
2019-09-01 |
description |
Due to the permanent discordance between the number of available liver grafts and the number of cases on
the waiting lists, attention was focused on developing different solutions in order to increase the number of
grafts. Once the technique of living donor has been proposed, the number of grafts increased but the gap
between the number of available grafts and the cases on the waiting list is still significant. Therefore attention
was focused on finding out other solutions such as splitting the graft or performing a domino liver transplant.
The procedure of domino transplant consists of harvesting a graft from a young patient with metabolic disorders in which a healthy graft will be used and implants it to a marginal receiver. The method seems to associate minimal risks for the marginal donor to develop the metabolic disorder especially if the donor suffers
from familial amyloid polyneuropathy; however, ethical issues in such cases are obvious. The aim of this
paper is to analyse both the benefits of domino liver transplant and the ethical issues of the procedure. |
topic |
domino liver transplant metabolic disorders survival ethical issues |
url |
https://revistemedicale.amaltea.ro/Romanian_MEDICAL_Journal/Revista_MEDICALA_ROMANA-2019-Nr.3/RMJ_2019_3_Art-12.pdf |
work_keys_str_mv |
AT nicolaebacalbasa benefitsandethicalissuesindominolivertransplant AT irinabalescu benefitsandethicalissuesindominolivertransplant AT adinacroitoru benefitsandethicalissuesindominolivertransplant AT simonadima benefitsandethicalissuesindominolivertransplant AT mihaelavilcu benefitsandethicalissuesindominolivertransplant AT iulianbrezean benefitsandethicalissuesindominolivertransplant |
_version_ |
1721169507670556672 |