Eosinophilic Esophagitis in Children in North-Eastern Poland
Background: An increase in the incidence of eosinophilic esophagitis worldwide is being observed in children. The aim of the study was to analyze the incidence, clinical manifestations, biochemical markers and endoscopic features of children with eosinophilic esophagitis in comparison to patients wi...
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doaj-1e12746f02d24a3d98234dc458e4324f2020-11-29T00:00:42ZengMDPI AGJournal of Clinical Medicine2077-03832020-11-0193869386910.3390/jcm9123869Eosinophilic Esophagitis in Children in North-Eastern PolandKatarzyna Zdanowicz0Magdalena Kucharska1Maria Elzbieta Sobaniec-Lotowska2Dariusz Marek Lebensztejn3Urszula Daniluk4Department of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, 15-274 Bialystok, PolandDepartment of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, 15-274 Bialystok, PolandDepartment of Medical Pathomorphology, Medical University of Bialystok, 15-274 Bialystok, PolandDepartment of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, 15-274 Bialystok, PolandDepartment of Pediatrics, Gastroenterology, Hepatology, Nutrition and Allergology, Medical University of Bialystok, 15-274 Bialystok, PolandBackground: An increase in the incidence of eosinophilic esophagitis worldwide is being observed in children. The aim of the study was to analyze the incidence, clinical manifestations, biochemical markers and endoscopic features of children with eosinophilic esophagitis in comparison to patients with non-eosinophilic esophagitis. Methods: This single-center retrospective study included newly diagnosed children with eosinophilic (EoE) and non-eosinophilic (non-EoE) esophagitis based on endoscopic and histopathological results between January 2013 and December 2018. Result: Among 433 of enrolled children with esophagitis, 36 (8.31%) were diagnosed with EoE (median age of 10 years). Male predominance and an increased percentage of allergy cases in the EoE group were noticed. Dysphagia was the only symptom that significantly differentiated both groups (<i>p</i> = 0.006). Endoscopic findings with relevant relationships with EoE included linear fissuring, decreased vascular pattern, trachealization and whitish exudates. No significant difference in the prevalence of other reported diseases between groups was observed. Conclusion: The results of EoE analysis in children from North-Eastern Poland did not differ from reports from other countries. The reported symptoms were not specific for EoE, and only dysphagia and some endoscopic lesions were helpful to differentiate children with EoE from non-EoE.https://www.mdpi.com/2077-0383/9/12/3869eosinophilic esophagitisesophagitiseosinophilallergydysphagiaesophagogastroduodenoscopy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Katarzyna Zdanowicz Magdalena Kucharska Maria Elzbieta Sobaniec-Lotowska Dariusz Marek Lebensztejn Urszula Daniluk |
spellingShingle |
Katarzyna Zdanowicz Magdalena Kucharska Maria Elzbieta Sobaniec-Lotowska Dariusz Marek Lebensztejn Urszula Daniluk Eosinophilic Esophagitis in Children in North-Eastern Poland Journal of Clinical Medicine eosinophilic esophagitis esophagitis eosinophil allergy dysphagia esophagogastroduodenoscopy |
author_facet |
Katarzyna Zdanowicz Magdalena Kucharska Maria Elzbieta Sobaniec-Lotowska Dariusz Marek Lebensztejn Urszula Daniluk |
author_sort |
Katarzyna Zdanowicz |
title |
Eosinophilic Esophagitis in Children in North-Eastern Poland |
title_short |
Eosinophilic Esophagitis in Children in North-Eastern Poland |
title_full |
Eosinophilic Esophagitis in Children in North-Eastern Poland |
title_fullStr |
Eosinophilic Esophagitis in Children in North-Eastern Poland |
title_full_unstemmed |
Eosinophilic Esophagitis in Children in North-Eastern Poland |
title_sort |
eosinophilic esophagitis in children in north-eastern poland |
publisher |
MDPI AG |
series |
Journal of Clinical Medicine |
issn |
2077-0383 |
publishDate |
2020-11-01 |
description |
Background: An increase in the incidence of eosinophilic esophagitis worldwide is being observed in children. The aim of the study was to analyze the incidence, clinical manifestations, biochemical markers and endoscopic features of children with eosinophilic esophagitis in comparison to patients with non-eosinophilic esophagitis. Methods: This single-center retrospective study included newly diagnosed children with eosinophilic (EoE) and non-eosinophilic (non-EoE) esophagitis based on endoscopic and histopathological results between January 2013 and December 2018. Result: Among 433 of enrolled children with esophagitis, 36 (8.31%) were diagnosed with EoE (median age of 10 years). Male predominance and an increased percentage of allergy cases in the EoE group were noticed. Dysphagia was the only symptom that significantly differentiated both groups (<i>p</i> = 0.006). Endoscopic findings with relevant relationships with EoE included linear fissuring, decreased vascular pattern, trachealization and whitish exudates. No significant difference in the prevalence of other reported diseases between groups was observed. Conclusion: The results of EoE analysis in children from North-Eastern Poland did not differ from reports from other countries. The reported symptoms were not specific for EoE, and only dysphagia and some endoscopic lesions were helpful to differentiate children with EoE from non-EoE. |
topic |
eosinophilic esophagitis esophagitis eosinophil allergy dysphagia esophagogastroduodenoscopy |
url |
https://www.mdpi.com/2077-0383/9/12/3869 |
work_keys_str_mv |
AT katarzynazdanowicz eosinophilicesophagitisinchildreninnortheasternpoland AT magdalenakucharska eosinophilicesophagitisinchildreninnortheasternpoland AT mariaelzbietasobanieclotowska eosinophilicesophagitisinchildreninnortheasternpoland AT dariuszmareklebensztejn eosinophilicesophagitisinchildreninnortheasternpoland AT urszuladaniluk eosinophilicesophagitisinchildreninnortheasternpoland |
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