ACUTE HEPATITIS С ON THE BACKGROUND OF LIVER Cirrhosis IN THE OUTCOME OF CHRONIC HEPATITIS C: CLINICAL CASE

ACUTE HEPATITIS С ON THE BACKGROUND OF LIVER Cirrhosis IN THE OUTCOME OF CHRONIC HEPATITIS C: CLINICAL CASE

A patient with Child-Pugh B cirrhosis as the outcome of chronic hepatitis C (HCV), genotype 1b was treated with ombitasvir/ paritaprevir/ritonavir/dasabuvir (Viekira Pak) and ribavirin (Ribavirin-SZ) for 12 weeks with achievement of sustained virological response. 48 weeks after the end of the antiv...

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Bibliographic Details
Main Authors: V. G. Morozov, E. S. Malova, L. M. Topornina, E. V. Jarkova, A. A. Ribkina, L. N. Finko, A. M. Kalishenko, P. E. Tkachenko, A. A. Ishmukhametov
Format: Article
Language:Russian
Published: Remedium Group LLC 2018-01-01
Series:Медицинский совет
Subjects:
acute hepatitis c
chronic hepatitis c
liver cirrhosis
antiviral treatment
Online Access:https://www.med-sovet.pro/jour/article/view/2240
Description
Summary:A patient with Child-Pugh B cirrhosis as the outcome of chronic hepatitis C (HCV), genotype 1b was treated with ombitasvir/ paritaprevir/ritonavir/dasabuvir (Viekira Pak) and ribavirin (Ribavirin-SZ) for 12 weeks with achievement of sustained virological response. 48 weeks after the end of the antiviral treatment the patient developed acute viral hepatitis with high level of liver aminotransferases caused by the hepatitis C virus genotype 3a. On day 18 of hospitalization antiviral therapy with sofosbuvir 400 mg per day and daclatasvir 60 mg per day for 12 weeks was administered. Drug tolerance was good, biochemical and sustained virological response was achieved.
ISSN:2079-701X
2658-5790

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