Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis

Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against Mycobacterium tuberculosis

Tuberculosis (TB) is the leading cause of death by a single infectious agent worldwide. One factor that contributes to the success of the microbe is the deficiency in immunomodulatory nutrients, such as vitamin A (retinol), which are prevalent in areas where TB is endemic. Clinical trials show that...

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Bibliographic Details
Main Authors: Elliot W. Kim, Avelino De Leon, Zhichun Jiang, Roxana A. Radu, Adrian R. Martineau, Edward D. Chan, Xiyuan Bai, Wen-Lin Su, Dennis J. Montoya, Robert L. Modlin, Philip T. Liu
Format: Article
Language:English
Published: American Society for Microbiology 2019-06-01
Series:mSphere
Subjects:
Mycobacterium tuberculosis
dendritic cells
transcellular metabolism
Online Access:https://doi.org/10.1128/mSphere.00327-19

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