Pneumocystis pneumonia in non-HIV patients

• Main Author: Vladimir B. Beloborodov
• Format: Article
• Language: Russian
• Published: ZAO "Consilium Medicum" 2019-03-01
• Series: Consilium Medicum
• Subjects: pneumocystis pneumonia; PcP therapy; PcP diagnosis
• Online Access: http://consilium.orscience.ru/en/archive/2019/vol-21-3-2019/pneumocystis-pneumonia-in-non-hiv-patients_5495/?element

The rates of pneumocystis pneumonia (PcP) are increasing in the HIV-negative susceptible population. Guidance for the diagnostic and treatment of PcP in patients with HIV, hematologic, and solid-organ transplant recipients is available Although for many other populations with immune disorders there remains an urgent need for recommendations. The main drug for treatment of PcP is trimethoprim/sulfamethoxazole. The possibilities of mycological diagnosis in routine clinical practice are very limited and require significant expansion. Outbreaks PcP in immunocompromised patients, likely caused by human-to-human spread, is highlighting the need for efficient infection control policies, sensitive diagnostic assays and Guidance for treatment in not-HIV patients.