Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing.
Connective Tissue Growth Factor (CTGF) and Transforming growth factor-β1 (TGF-β1) are key growth factors in regulating corneal scarring. Although CTGF was induced by TGF-β1 and mediated many of fibroproliferative effects of TGF-β1, the signaling pathway for CTGF production in corneal scarring remain...
Main Authors: | Long Shi, Yuan Chang, Yongmei Yang, Ying Zhang, Fu-Shin X Yu, Xinyi Wu |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3283717?pdf=render |
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