The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF

The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF

Small, cysteine-rich and cationic antimicrobial proteins (AMPs) from filamentous ascomycetes represent ideal bio-molecules for the development of next-generation antifungal therapeutics. They are promising candidates to counteract resistance development and may complement or even replace current sma...

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Bibliographic Details
Main Authors: Christoph Sonderegger, Györgyi Váradi, László Galgóczy, Sándor Kocsubé, Wilfried Posch, Attila Borics, Sandrine Dubrac, Gábor K. Tóth, Doris Wilflingseder, Florentine Marx
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
Penicillium chrysogenum antifungal protein PAF
gamma(γ-) core
antimicrobial proteins
antimicrobial peptides
Candida albicans
biofilm
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01655/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01655/full

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