Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity

Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity

Neurospora crassa cpc-1 and Saccharomyces cerevisiae GCN4 are homologs specifying transcription activators that drive the transcriptional response to amino acid limitation. The cpc-1 mRNA contains two upstream open reading frames (uORFs) in its >700-nucleotide (nt) 5′ leader, and its expression i...

Full description

Bibliographic Details
Main Authors: Ivaylo P. Ivanov, Jiajie Wei, Stephen Z. Caster, Kristina M. Smith, Audrey M. Michel, Ying Zhang, Andrew E. Firth, Michael Freitag, Jay C. Dunlap, Deborah Bell-Pedersen, John F. Atkins, Matthew S. Sachs, John W. Taylor
Format: Article
Language:English
Published: American Society for Microbiology 2017-06-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/3/e00844-17

Internet

http://mbio.asm.org/cgi/content/full/8/3/e00844-17

Similar Items