Differential T cell response against BK virus regulatory and structural antigens: A viral dynamics modelling approach.
BK virus (BKV) associated nephropathy affects 1-10% of kidney transplant recipients, leading to graft failure in about 50% of cases. Immune responses against different BKV antigens have been shown to have a prognostic value for disease development. Data currently suggest that the structural antigens...
Main Authors: | Arturo Blazquez-Navarro, Thomas Schachtner, Ulrik Stervbo, Anett Sefrin, Maik Stein, Timm H Westhoff, Petra Reinke, Edda Klipp, Nina Babel, Avidan U Neumann, Michal Or-Guil |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-05-01
|
Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1005998 |
Similar Items
-
beadplexr: reproducible and automated analysis of multiplex bead assays
by: Ulrik Stervbo, et al.
Published: (2018-11-01) -
BKV Clearance Time Correlates With Exhaustion State and T-Cell Receptor Repertoire Shape of BKV-Specific T-Cells in Renal Transplant Patients
by: Ulrik Stervbo, et al.
Published: (2019-04-01) -
Repeated Changes to the Gravitational Field Negatively Affect the Serum Concentration of Select Growth Factors and Cytokines
by: Ulrik Stervbo, et al.
Published: (2019-04-01) -
The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains
by: Mikalai Nienen, et al.
Published: (2019-04-01) -
Sex-Associated Differences in Cytomegalovirus Prevention: Prophylactic Strategy is Potentially Associated With a Strong Kidney Function Impairment in Female Renal Transplant Patients
by: Arturo Blazquez-Navarro, et al.
Published: (2020-12-01)