ANT2-defective fibroblasts exhibit normal mitochondrial bioenergetics

ANT2-defective fibroblasts exhibit normal mitochondrial bioenergetics

Adenine nucleotide translocase 2 (ANT2) transports glycolytic ATP across the inner mitochondrial membrane. Patients with ANT2 deletion were recently reported. We aimed at characterizing mitochondrial functions in ANT2-defective fibroblasts. In spite of ANT2 expression in fibroblasts, we observed no...

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Bibliographic Details
Main Authors: Dolly Prabhu, Amy C. Goldstein, Riyad El-Khoury, Malgorzata Rak, Lia Edmunds, Pierre Rustin, Jerry Vockley, Manuel Schiff
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
Adenine nucleotide translocase 2
ANT2
SLC25A5
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426915000166

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