Protective Effect of Baicalin against <i>Clostridioides difficile</i> Infection in Mice

Protective Effect of Baicalin against <i>Clostridioides difficile</i> Infection in Mice

This study investigated the prophylactic and therapeutic efficacies of baicalin (BC), a plant-derived flavone glycoside, in reducing the severity of <i>Clostridioides difficile</i> infection (CDI) in a mouse model. In the prophylactic trial, C57BL/6 mice were provided with BC (0, 11, and...

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Bibliographic Details
Main Authors: Abraham Joseph Pellissery, Poonam Gopika Vinayamohan, Deepa Ashwarya Kuttappan, Neha Mishra, Breno de Oliveira Fragomeni, Kendra Maas, Shankumar Mooyottu, Kumar Venkitanarayanan
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Antibiotics
Subjects:
<i>Clostridioides difficile</i>
baicalin
microbiome
gut dysbiosis
mouse model
Online Access:https://www.mdpi.com/2079-6382/10/8/926

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