Searching for the Achilles heel of FOXP3

FOXP3 is a multifaceted transcription factor with a major role in the control of immune homeostasis mediated by T regulatory cells (Treg). The immunoregulatory function of FOXP3 may hinder the induction of immune responses against cancer and infectious agents, and thus, development of inhibitors of...

Full description

Bibliographic Details
Main Authors: Teresa eLozano, Noelia eCasares, Juan José Lasarte
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00294/full