CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW

CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW

A comparison of the possibilities of using various neurotropic radiopharmaceuticals for scintigraphic evaluation of cerebral perfusion. In the whole range of radiopharmaceuticals used to diagnose cerebral blood flow disorders, there are Ceretec (99mTc-hexamethylpropyleneamine) and Neurolite (N,N-1,2...

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Main Authors: N. Yu. N.Yu. Efimova, N. G. Krivonogov, Yu. B. Lishmanov, I. Yu. Efimova
Format: Article
Language:English
Published: LUCHEVAYA DIAGNOSTIKA, LLC 2017-03-01
Series:Вестник рентгенологии и радиологии
Subjects:
review
<sub>99m</sub>tc-hexamethylpropyleneamine
n,n-1,2-ethylenediylbis-l-cysteine-diethyl ether
cerebral perfusion
Online Access:https://www.russianradiology.ru/jour/article/view/196
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spelling doaj-1eb15a47c8bb44e78972cfd1c9da03a02021-09-15T15:32:23ZengLUCHEVAYA DIAGNOSTIKA, LLCВестник рентгенологии и радиологии0042-46762619-04782017-03-01981444910.20862/0042-4676-2017-98-1-44-49162CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOWN. Yu. N.Yu. Efimova0N. G. Krivonogov1Yu. B. Lishmanov2I. Yu. Efimova3Сardiology Research Institute, ul. Kievskaya, 111a, Tomsk, 634012, Russian Federation; Tomsk Polytechnic University, prospect Lenina, 30, Tomsk, 634050, Russian FederationСardiology Research Institute, ul. Kievskaya, 111a, Tomsk, 634012, Russian FederationСardiology Research Institute, ul. Kievskaya, 111a, Tomsk, 634012, Russian Federation; Tomsk Polytechnic University, prospect Lenina, 30, Tomsk, 634050, Russian FederationСardiology Research Institute, ul. Kievskaya, 111a, Tomsk, 634012, Russian FederationA comparison of the possibilities of using various neurotropic radiopharmaceuticals for scintigraphic evaluation of cerebral perfusion. In the whole range of radiopharmaceuticals used to diagnose cerebral blood flow disorders, there are Ceretec (99mTc-hexamethylpropyleneamine) and Neurolite (N,N-1,2-ethylenediylbis-L-cysteine-diethyl ether), which are the most optimal agents. Due to their high cost and related radiation exposure, the radiopharmaceuticals 123І-IMP (123I-isopropyl-iodoamphetamine) and 201Tl-DDC (diethyldithiocarbamate) labeled with thallium-201 virtually minimize the possibilities of being used in daily clinical practice. Fixation of 99mTc-DDC in the brain proves to be short-term, which is insufficient for tomoscintigraphy studies. Literature has been sought in the Scopus, Web of Scince, Pubmed, EMBASE, and Russian Science Citation Index databases.https://www.russianradiology.ru/jour/article/view/196review<sub>99m</sub>tc-hexamethylpropyleneaminen,n-1,2-ethylenediylbis-l-cysteine-diethyl ethercerebral perfusion
collection DOAJ
language English
format Article
sources DOAJ
author N. Yu. N.Yu. Efimova
N. G. Krivonogov
Yu. B. Lishmanov
I. Yu. Efimova
spellingShingle N. Yu. N.Yu. Efimova
N. G. Krivonogov
Yu. B. Lishmanov
I. Yu. Efimova
CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW
Вестник рентгенологии и радиологии
review
<sub>99m</sub>tc-hexamethylpropyleneamine
n,n-1,2-ethylenediylbis-l-cysteine-diethyl ether
cerebral perfusion
author_facet N. Yu. N.Yu. Efimova
N. G. Krivonogov
Yu. B. Lishmanov
I. Yu. Efimova
author_sort N. Yu. N.Yu. Efimova
title CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW
title_short CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW
title_full CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW
title_fullStr CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW
title_full_unstemmed CURRENT POSSIBILITIES OF USING RADIOPHARMACEUTICALS TO EVALUATE CEREBRAL BLOOD FLOW
title_sort current possibilities of using radiopharmaceuticals to evaluate cerebral blood flow
publisher LUCHEVAYA DIAGNOSTIKA, LLC
series Вестник рентгенологии и радиологии
issn 0042-4676
2619-0478
publishDate 2017-03-01
description A comparison of the possibilities of using various neurotropic radiopharmaceuticals for scintigraphic evaluation of cerebral perfusion. In the whole range of radiopharmaceuticals used to diagnose cerebral blood flow disorders, there are Ceretec (99mTc-hexamethylpropyleneamine) and Neurolite (N,N-1,2-ethylenediylbis-L-cysteine-diethyl ether), which are the most optimal agents. Due to their high cost and related radiation exposure, the radiopharmaceuticals 123І-IMP (123I-isopropyl-iodoamphetamine) and 201Tl-DDC (diethyldithiocarbamate) labeled with thallium-201 virtually minimize the possibilities of being used in daily clinical practice. Fixation of 99mTc-DDC in the brain proves to be short-term, which is insufficient for tomoscintigraphy studies. Literature has been sought in the Scopus, Web of Scince, Pubmed, EMBASE, and Russian Science Citation Index databases.
topic review
<sub>99m</sub>tc-hexamethylpropyleneamine
n,n-1,2-ethylenediylbis-l-cysteine-diethyl ether
cerebral perfusion
url https://www.russianradiology.ru/jour/article/view/196
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AT ngkrivonogov currentpossibilitiesofusingradiopharmaceuticalstoevaluatecerebralbloodflow
AT yublishmanov currentpossibilitiesofusingradiopharmaceuticalstoevaluatecerebralbloodflow
AT iyuefimova currentpossibilitiesofusingradiopharmaceuticalstoevaluatecerebralbloodflow
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