Lysozyme nephropathy in chronic myelomonocytic leukemia

Abstract Lysozyme nephropathy is a frequently unrecognized cause of renal disease in chronic myelomonocytic leukemia and may serve as a novel indication for treatment in this patient population. We demonstrate that in newly diagnosed CMML patients, plasma lysozyme levels are positively correlated wi...

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Main Authors: Ami B. Patel, Rodney R. Miles, Michael W. Deininger
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.2188
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spelling doaj-1eb97258584d45619d65c42b64d824882020-11-25T00:17:27ZengWileyClinical Case Reports2050-09042019-06-01761263126410.1002/ccr3.2188Lysozyme nephropathy in chronic myelomonocytic leukemiaAmi B. Patel0Rodney R. Miles1Michael W. Deininger2Division of Hematology and Hematologic Malignancies University of Utah Salt Lake City UtahDepartment of Pathology, ARUP Laboratories University of Utah Salt Lake City UtahDivision of Hematology and Hematologic Malignancies University of Utah Salt Lake City UtahAbstract Lysozyme nephropathy is a frequently unrecognized cause of renal disease in chronic myelomonocytic leukemia and may serve as a novel indication for treatment in this patient population. We demonstrate that in newly diagnosed CMML patients, plasma lysozyme levels are positively correlated with both absolute monocyte count and serum creatinine.https://doi.org/10.1002/ccr3.2188hematologynephrologyoncology
collection DOAJ
language English
format Article
sources DOAJ
author Ami B. Patel
Rodney R. Miles
Michael W. Deininger
spellingShingle Ami B. Patel
Rodney R. Miles
Michael W. Deininger
Lysozyme nephropathy in chronic myelomonocytic leukemia
Clinical Case Reports
hematology
nephrology
oncology
author_facet Ami B. Patel
Rodney R. Miles
Michael W. Deininger
author_sort Ami B. Patel
title Lysozyme nephropathy in chronic myelomonocytic leukemia
title_short Lysozyme nephropathy in chronic myelomonocytic leukemia
title_full Lysozyme nephropathy in chronic myelomonocytic leukemia
title_fullStr Lysozyme nephropathy in chronic myelomonocytic leukemia
title_full_unstemmed Lysozyme nephropathy in chronic myelomonocytic leukemia
title_sort lysozyme nephropathy in chronic myelomonocytic leukemia
publisher Wiley
series Clinical Case Reports
issn 2050-0904
publishDate 2019-06-01
description Abstract Lysozyme nephropathy is a frequently unrecognized cause of renal disease in chronic myelomonocytic leukemia and may serve as a novel indication for treatment in this patient population. We demonstrate that in newly diagnosed CMML patients, plasma lysozyme levels are positively correlated with both absolute monocyte count and serum creatinine.
topic hematology
nephrology
oncology
url https://doi.org/10.1002/ccr3.2188
work_keys_str_mv AT amibpatel lysozymenephropathyinchronicmyelomonocyticleukemia
AT rodneyrmiles lysozymenephropathyinchronicmyelomonocyticleukemia
AT michaelwdeininger lysozymenephropathyinchronicmyelomonocyticleukemia
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