Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting.

Genomic imprinting is a normal process that causes genes to be expressed according to parental origin. The selective advantage conferred by imprinting is not understood but is hypothesised to act on dosage-critical genes. Here, we report a unique model in which the consequences of a single, double,...

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Bibliographic Details
Main Authors: Simao Teixeira da Rocha, Marika Charalambous, Shau-Ping Lin, Isabel Gutteridge, Yoko Ito, Dionne Gray, Wendy Dean, Anne C Ferguson-Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2640098?pdf=render