Cell Surface Heparan Sulfate Proteoglycans Mediate the Internalization of PDX-1 Protein

Although islet transplantation is a promising therapeutic option for the treatment of type 1 diabetes, the shortage of suitable donor tissues remains a major obstacle. Pancreatic stem/progenitor cells residing within the ductal epithelium have been used to generate human islet-like clusters, but the...

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Bibliographic Details
Main Authors: Michiko Ueda, Shinichi Matsumoto, Shuji Hayashi, Naoya Kobayashi, Hirofumi Noguchi M.D., Ph.D.
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000008783906892