Antimicrobial effects of nitric oxide in murine models of Klebsiella pneumonia

Rationale: Inhalation of nitric oxide (NO) exerts selective pulmonary vasodilation. Nitric oxide also has an antimicrobial effect on a broad spectrum of pathogenic viruses, bacteria and fungi. Objectives: The aim of this study was to investigate the effect of inhaled NO on bacterial burden and disea...

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Bibliographic Details
Main Authors: Steffen B. Wiegand, Lisa Traeger, Huan K. Nguyen, Kaitlyn R. Rouillard, Anna Fischbach, Francesco Zadek, Fumito Ichinose, Mark H. Schoenfisch, Ryan W. Carroll, Donald B. Bloch, Warren M. Zapol
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720310314