MicroRNA regulation of vascular function

MicroRNA regulation of vascular function

MicroRNAs (miRNAs) are small non-coding RNAs that orchestrate genetic networks by modulating gene expression. Given their importance in vascular development, homeostasis and diseases, along with the technical feasibility in deploying their function in vivo, the so-called ‘vascular miRNAs’ have becom...

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Bibliographic Details
Main Authors: David Mellis, Andrea Caporali
Format: Article
Language:English
Published: Bioscientifica 2019-07-01
Series:Vascular Biology
Subjects:
angiogenesis
endothelium
signalling
Online Access:https://doi.org/10.1530/VAB-19-0009
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spelling doaj-1edb1d182494480aabfd8a96fec8b7812020-11-25T02:29:51ZengBioscientificaVascular Biology2516-56582516-56582019-07-0111H41H46https://doi.org/10.1530/VB-19-0009MicroRNA regulation of vascular functionDavid Mellis0Andrea Caporali1University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UKUniversity/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UKMicroRNAs (miRNAs) are small non-coding RNAs that orchestrate genetic networks by modulating gene expression. Given their importance in vascular development, homeostasis and diseases, along with the technical feasibility in deploying their function in vivo, the so-called ‘vascular miRNAs’ have become key targets for therapeutic intervention. Herein, we have summarised the state-of-the-art on vascular miRNAs and we have discussed the role miRNA biogenesis and the extracellular vesicles (EVs) miRNA transport in vascular biology.https://doi.org/10.1530/VAB-19-0009angiogenesisendotheliumsignalling
collection DOAJ
language English
format Article
sources DOAJ
author David Mellis
Andrea Caporali
spellingShingle David Mellis
Andrea Caporali
MicroRNA regulation of vascular function
Vascular Biology
angiogenesis
endothelium
signalling
author_facet David Mellis
Andrea Caporali
author_sort David Mellis
title MicroRNA regulation of vascular function
title_short MicroRNA regulation of vascular function
title_full MicroRNA regulation of vascular function
title_fullStr MicroRNA regulation of vascular function
title_full_unstemmed MicroRNA regulation of vascular function
title_sort microrna regulation of vascular function
publisher Bioscientifica
series Vascular Biology
issn 2516-5658
2516-5658
publishDate 2019-07-01
description MicroRNAs (miRNAs) are small non-coding RNAs that orchestrate genetic networks by modulating gene expression. Given their importance in vascular development, homeostasis and diseases, along with the technical feasibility in deploying their function in vivo, the so-called ‘vascular miRNAs’ have become key targets for therapeutic intervention. Herein, we have summarised the state-of-the-art on vascular miRNAs and we have discussed the role miRNA biogenesis and the extracellular vesicles (EVs) miRNA transport in vascular biology.
topic angiogenesis
endothelium
signalling
url https://doi.org/10.1530/VAB-19-0009
work_keys_str_mv AT davidmellis micrornaregulationofvascularfunction
AT andreacaporali micrornaregulationofvascularfunction
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