Hereditary angioedema type II and dental extraction: case report and literature review

• Main Authors: Aroufi Wafa, Pavageau Claire, Sturque Julie, Zlowodzki Aude-Sophie, Georgescou Gabriela, Denis Frédéric
• Format: Article
• Language: English
• Published: EDP Sciences 2020-01-01
• Series: Journal of Oral Medicine and Oral Surgery
• Subjects: angioedema; hereditary; dental
• Online Access: https://www.jomos.org/articles/mbcb/full_html/2020/03/mbcb200045/mbcb200045.html

Introduction: The hereditary angioedema of type II (HAE type II) is a disease which, in the case of invasive acts such as dental extractions, can trigger potentially fatal laryngeal edema. Observation: A 64-year-old man presented to the hospital to perform dental extractions. The anamnesis revealed a history of hereditary angioedema of type II. The National Reference Center for Angioedema (CREAK) recommended a prophylactic protocol before performing this traumatic dental procedure in order to reduce the risk of post-operative edema. Discussion: The HAE type II is under- or misdiagnosed. The literature reports cases of death related to dental procedures in patients unaware of being a carrier of the disease. Conclusion: In case of certain evocative signs (recurrent edema, abdominal pain, family history, etc.), the odontologist must play an active role in the early detection of HAE type II.